Publications
- Bouchal, P., Dvořáková, M., Roumeliotis, T., Bortlíček, Z., Ihnatová, I., Procházková, I., Ho, J.T.C., Maryáš, J., Imrichová, H., Budinská, E., Vyzula, R., Garbis, S.D., Vojtěšek, B., Nenutil, R. Combined Proteomics and Transcriptomics Identifies Carboxypeptidase B1 and Nuclear Factor κB (NF-κB) Associated Proteins as Putative Biomarkers of Metastasis in Low Grade Breast Cancer. Mol Cell Proteomics 2015;14(7):1814-1830. (IF: 6.564).
- Cizkova, M.Susini, A., Vacher, S., Cizeron-Clairac, G., Andrieu, C., Driouch, K., Fourme, E., Lidereau R., Biéche, A.I. Pik3ca mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups. Breast Cancer Research. 2012, 14(1): R28. (IF: 5.245).
- Cizkova, M., Dujaric, M.-E., Lehmann-Che, J., Scott, V., Tembo, O., Asselain, B., Pierga, J.Y., Marty, M., de Cremoux, P., Spyratos, F., Biéche, A.I. Outcome impact of PIK3CA mutations in HER2-positive breast cancer patients treated with trastuzumab. British Journal of Cancer. 2013;108(9):1807-1809. (IF: 5.082).
- Janeckova, H., Hron, K., Wojtowicz, P., Hlidkova, E., Baresova, A., Friedecky, D., Zidkova, L., Hornik, P., Behulova, D., Prochazkova, D., Vinohradska, H., Peskova, K., Bruheim, P., Smolka, V., Stastna, S., Adam, A.T. Targeted metabolomic analysis of plasma samples for the diagnosis of inherited metabolic disorders. Journal of Chromatography A. 2012;1226(-):11-17. (IF: 4.194).
- Němejcová, K., Kenny, S.L., Laco, J., Škapa, P., Staněk, L., Zikán, M., Kleiblová, P., McCluggage, W.G., Dundr, P. Atypical Polypoid Adenomyoma of the Uterus: An Immunohistochemical and Molecular Study of 21 Cases. Am J Surg Pathol 2015;39(8):1148-55.(IF: 4.9).
- Oplustilova, L., Wolanin, K., Mistrik, M., Korinkova, G., Simkova, D., Bouchal, J., Lenobel, R., Bartkova, J., Lau, A., O´Connor, M.J., Lukas, J., Bartek, J. Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment. Cell Cycle. 2012;11(20):3837-3805. (IF: 5.321).
- Ryška, A. Molecular pathology in real time. Cancer Metastasis Rev 2016;35(1):129-140. (IF: 5,316).
- Sevcik, J., Falk, M., Macurek, L., Kleiblova, P., Lhota, F., Hojny, J., Stefancikova, L., Janatova, M., Bartek, J., Stribrna, J., Hodny, Z., Jezkova, L., Pohlreich, P. Kleibl Z. Expression of human BRCA1Δ17-19 alternative splicing variant with a truncated BRCT domain in MCF-7 cells results in impaired assembly of DNA repair complexes and aberrant DNA damage response. Cellular Signalling. 2013;25(5):1186-1193. (IF:4.304).
- Vašatová, M., Pudil, R., Horáček, J., Büchler, T. Current Applications of Cardiac Troponin T for the Diagnosis of Myocardial Damage. Advances in Clinical Chemistry. 2013;61:33-65. (IF: 4.302).
- Ranc, V., Srovnal, J., Kvitek L., Hajdúch, M. Discrimination of circulating tumor cells of breast cancer and colorectal cancer from normal human mononuclear cells using Raman spectroscopy. Analyst. 2013;138(20):5983-5988. (IF: 3.969)
Patents
- ETH Zurich; Palacky University, Olomouc. Biomarker assay and uses thereof for diagnosis, therapy selection, and prognosis of cancer. Inventor: SURINOVA, S., R. AEBERSOLD, M. HAJDUCH, J. SROVNAL, J. DRABEK a L. RADOVA. WIPO. Patent application, WO 2013152989 A2. 2013-10-17.
- Palacky University, Olomouc; Institute of Animal Physiology and Genetics ASCR, v.v.i. Libechov. Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance. Inventor: KOLLAREDDY, M.R., M. HAJDUCH, P. DZUBAK, J. SROVNAL, R. HRABAKOVA a H. KOVAROVA. EPO. Patent application, EP 2602330 A1. 2013-06-12.
- Mrkvicová, M., Valík, D., Zdražilová Dubská L. Stanovení mutací v genu TPMT: detekce na základě mutačně specifické real-time PCR. 2014. N/A - Uplatněná certifikovaná metodika. RIV/00209805:_____/14:#0000497.
- Palacky University, Olomouc; Institute of Animal Physiology and Genetics ASCR, v.v.i. Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors. Vynálezce: KOLLAREDDY, M. R., M. HAJDUCH, P. DZUBAK, J. SROVNAL, R. HRABAKOVA a H. KOVAROVA. EPO. Patentový spis, EP 2788504 B1. 2016-08-17.
- Palacky University, Olomouc. Sample containters, Inventor: DŽUBÁK, P. a M. HAJDÚCH. EUIPO. Utility pattern, RCD 003039577-0001, 2016-03-23.
- Palacky University, Olomouc. Culturing kit for microscopy of adhesively growing cell structures. Inventors: MISTRÍK M. a J. BÁRTEK.Utility pattern. CZ 29265, 2016-03-15.
- Palacky University, Olomouc. Mobile hyperbaric miniature chambre. Inventor: KOLÁŘOVÁ H., BAJGAR R., TOMÁNKOVÁ K., BOLEK L., DEJMEK J., BOLEK M., RŮŽIČKA J. a J. BENEŠ. Patent application, CZ 305989, 2016-04-27.
- Palacky University, Olomouc. Stand for magnetic separation of ferromagnetic Inventor: KOBERNA K. a A. LIGASOVÁ. Industrial pattern, CZ 36681, 2016-03-02.
- Palacky University, Olomouc. Device for magnetic separation of ferromagnetic particles, kit for magnetic separation of the particles, method of separation of magnetic particles from a solution and use thereof. Inventor: KOBERNA K. a A. LIGASOVÁ. Patent application, CZ 306187, 2016-08-03.
Projects
- LM2010004: BBMRI-CZ in the building of the Czech part of a large distributed research infrastructure of pan-European importance: the creation and operation of the network of banks of biological material for biomedical research,
- LM2011024: EATRIS-CZ (Enhancement and Connection of the Czech Translational Medicine Infrastructures to the European Advanced Translational Medicine Infrastructure),
- LM2015089: Bank of Clinical Specimens, Ministry of Education, Youth and Sports.
- IGA MH CR NT/13549-4/2012: Vytvoření diagnostické sady cirkulujících mikroRNA pro neinvazivní časnou diagnostiku a sledování pacientů s kolorektálním karcinomem. Ondřej Slabý, Ph.D.
- MEYS MSM0021620808: Research plan and follow up research of ovarian cancer - First Faculty of Medicine, Charles University in Prague. Luděk Záveský, Ph.D.
- OP R&D pI CZ.1.05/2.1.00/03.0101: Regional Centre for Applied Molecular Oncology. Doc. MUDr. Dalibor Valík, Ph.D.
- P206/12/G151: Center of novel approaches to bioanalysis and molecular diagnostics. RNDr. Bořivoj Vojtěšek, DrSc.
- GAČR 13-00956S: Emerging roles for the proteins of Anterior Gradient family in cancer development.Roman Hrstka, Ph.D.
- GAČR 14-24931P: Electrochemical methods for bioanalysis of nucleic acids and their application in cancer diagnostics. Mgr. Martin Bartošík, Ph.D.
- GAČR 16-04496S: Glycobiological investigations pertaining to biomolecular differentiation of mammary carcinomas. prof. RNDr. Miloš Novotný DrSc.
- GAČR 14-19250S: A novel panel of proteins associated with lymph node status in low-grade breast cancer: Clinical verification and role in tumor cell invasiveness. Mgr. Pavel Bouchal, Ph.D.
- IGA MH CZ NT14602-3-2013: p63 and p73 proteins as predictive markers in clinical oncology. Mgr. Jitka Holčáková, Ph.D.
- IGA MH CR NT/13794-4/2012: The analysis of chaperone system and identification of new biomarkers associated with gynecological malignancies. RNDr. Bořivoj Vojtěšek, DrSc.
- GAČR 301/10/1615: AGR2 protein family: implication for cancer biology. Mgr. Roman Hrstka, Ph.D.
- Grant project NT 14150-3/2013: Ovlivnění kolorektálního karcinomu biologickou léčbou - in vitro studie. Prof. MUDr. Aleš Ryška, Ph.D.
- Tissue engineering of genetically competent corneal/conjunctival cells for subsequent grafting in human medicine, Czech-Norwegian Research Program, Ministry of Education, Youth and Sports, MSMT-28477/2014, project: 7F14156 (BBMRI participates on retrieval and storage of eye tissue for research.
- INFLA-CARE – Understanding inflammation-associated tumorigenesis for the rational design of novel anti-cancer therapeutic strategies. (7. FP)
- A/CZ0046/1/0022 - Research of new compounds as potential drugs against childhood cancers (EEA grants/Norway grants)
- Enhancement of Research Infrastructure for Individualised Therapy of Chronically Sick Children (EEA grants/Norway grants)
- 676550: ADOPT BBMRI-ERIC (implementation and operation of the gateway for health into BBMRI-ERIC).
- 654142: EGI-ENGAGE (Engaging the EGI Community towards an Open Science Commons)